Answer
Coadministration of multiple doses of rifampin, a strong CYP3A4 inducer, decreases belumosudil mesilate (Rezurock) Cmax by 59% and AUC by 72%; the recommended belumosudil dose is increased to 200 mg twice daily.
Sources for this answer
- REZUROCK 200 mg film-coated tablets.SANOFI · emc · SmPC §4.5 Interaction with other medicinal products · Version 8Document updated
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