Answer
Repeated rifampin at 600 mg once daily, a strong CYP3A inducer, increased cabazitaxel clearance by 21% and decreased exposure (AUC) by 17%, so concurrent use should be avoided.
Sources for this answer
- Cabazitaxel 60 mg Concentrate and Solvent For Solution For InfusionDr. Reddy's Laboratories (UK) Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 5Document updated
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