raltegravir · Medicine question

How does raltegravir prevent HIV-1 from replicating?

iatroX medicinesPublished 8 November 2026

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Raltegravir inhibits the catalytic activity of HIV-1 integrase, preventing integration of the viral genome into the host cell genome, without which HIV cannot direct production of new infectious viral particles.

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Raltegravir 600 mg film-coated tabletsLupin Healthcare (UK) Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 1Document updated 24 October 2024

Sources checked 8 November 2026

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Are any pharmaceutical incompatibilities specified for the Lupin Healthcare (UK) Ltd raltegravir 600 mg film-coated tablet product?Are there any special disposal requirements for the Lupin Healthcare (UK) Ltd raltegravir 600 mg film-coated tablet product?Can omeprazole be co-administered with raltegravir 1,200 mg once daily?Has depression, including suicidal thoughts or behaviours, been reported with raltegravir?How can raltegravir affect the ability to drive or use machines?

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