Answer
Rabeprazole sodium specifically inhibits the H+/K+-ATPase proton pump, producing dose-related inhibition of basal and stimulated stomach acid secretion regardless of the stimulus, after concentrating in acidic parietal cells and converting to an active sulphenamide that reacts with proton-pump cysteines.
Sources for this answer
- Pariet 10mg tabletEisai Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 27Document updated
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