protein c · Medicine question

How does protein C in Ceprotin reduce thrombin formation?

iatroX medicinesPublished 8 November 2026

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Protein C in Ceprotin is converted by the thrombin/thrombomodulin complex on endothelial surfaces into activated protein C, which inactivates activated factors V and VIII, reducing thrombin formation.

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CEPROTIN 1000 IU powder and solvent for solution for injectionTakeda UK Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 8Document updated 20 January 2023

Sources checked 8 November 2026

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Can Ceprotin (protein C) cause severe allergic reactions?Can Ceprotin (protein C) transmit infections despite donor screening and manufacturing precautions?Has the safety and efficacy of Ceprotin (protein C) been established in patients with kidney or liver impairment?How much sodium does each vial of Ceprotin 1000 IU protein C contain?Is it known whether protein C passes into breast milk during Ceprotin treatment?What excipients are present in Ceprotin protein C powder?

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