Answer
Concurrent probenecid administration prolongs the half-life and reduces renal clearance of both piperacillin and tazobactam, without affecting their peak plasma concentrations.
Sources for this answer
- Piperacillin/Tazobactam 4 g / 0.5 g powder for solution for infusionAurobindo Pharma - Milpharm Ltd. · emc · SmPC §4.5 Interaction with other medicinal products · Version 10Document updated
Sources checked