Answer
Phenytoin sodium appears to promote sodium efflux from neurons, stabilising their threshold against hyperexcitability and reducing post-tetanic potentiation at synapses, thereby preventing seizure foci in the motor cortex from activating adjacent cortical areas.
Sources for this answer
- Phenytoin Hospira 50 mg/ml Injection BPHospira UK Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 25Document updated
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