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Medicines etoposideQuestion & answer

etoposide · Medicine question

How does phenytoin affect etoposide clearance and efficacy in adults?

iatroX medicinesPublished 8 November 2026

The answer

Answer

In adults, concomitant phenytoin therapy is associated with increased etoposide clearance and reduced etoposide efficacy.

Sources for this answer

Etoposide 50 mg capsule, softNeon Healthcare Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 5Document updated 25 March 2024

Sources checked 8 November 2026

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