pegzilarginase · Medicine question

How does pegzilarginase reduce plasma arginine in people with arginase 1 deficiency?

Name: How does pegzilarginase reduce plasma arginine in people with arginase 1 deficiency?
Published: 2026-11-08T01:59:23.331Z

iatroX medicinesPublished 8 November 2026

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Pegzilarginase substitutes for deficient human arginase 1 enzyme activity, rapidly and sustainably reducing plasma arginine by converting it to urea and ornithine.

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Loargys 5 mg/ml solution for injection/infusionImmedica · emc · SmPC §5.1 Pharmacodynamic properties · Version 4Document updated 18 November 2025

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