Answer
Paclitaxel albumin promotes microtubule assembly from tubulin dimers and prevents depolymerisation, blocking the dynamic reorganisation required for interphase and mitosis while inducing abnormal microtubule bundles throughout the cell cycle and multiple asters during mitosis.
Sources for this answer
- Paclitaxel (Pazenir) 5 mg/ml Powder for Dispersion for InfusionTeva UK Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 6Document updated
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