Answer
Oritavancin diphosphate inhibits bacterial cell-wall polymerisation by binding peptidoglycan precursor stem peptides, inhibits cell-wall crosslinking by binding peptide bridging segments, and disrupts membrane integrity, causing depolarisation, permeabilisation and rapid cell death.
Sources for this answer
- Tenkasi 400 mg powder for concentrate for solution for infusionA. Menarini Farmaceutica Internazionale SRL · emc · SmPC §5.1 Pharmacodynamic properties · Version 4Document updated
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