olipudase alfa · Medicine question

How does olipudase alfa affect sphingomyelin accumulation in the organs of patients with acid sphingomyelinase deficiency?

Name: How does olipudase alfa affect sphingomyelin accumulation in the organs of patients with acid sphingomyelinase deficiency?
Published: 2026-11-08T14:30:33.113Z

iatroX medicinesPublished 8 November 2026

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Olipudase alfa is a recombinant human acid sphingomyelinase that reduces sphingomyelin accumulation in the organs of patients with acid sphingomyelinase deficiency (ASMD).

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Xenpozyme 20 mg powder for concentrate for solution for infusionSANOFI · emc · SmPC §5.1 Pharmacodynamic properties · Version 8Document updated 18 February 2026

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