Answer
Ofatumumab binds to CD20 and induces lysis of CD20-positive B cells primarily through complement-dependent cytotoxicity and, to a lesser extent, antibody-dependent cell-mediated cytotoxicity.
Sources for this answer
- Kesimpta 20 mg solution for injection in pre-filled penNovartis Pharmaceuticals UK Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 7Document updated
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