Answer
Obeticholic acid activates the farnesoid X receptor (FXR), reducing bile acid levels in liver cells by suppressing new bile acid synthesis from cholesterol and increasing bile acid transport out of those cells.
Sources for this answer
- Ocaliva 10 mg film-coated tabletsADVANZ Pharma · emc · SmPC §5.1 Pharmacodynamic properties · Version 3Document updated
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