Answer
Nonacog alfa replaces deficient factor IX in haemophilia B; once activated, it works with activated factor VIII to activate factor X, ultimately producing thrombin, which converts fibrinogen into fibrin so a clot can form.
Sources for this answer
- BeneFIX 250 IU powder and solvent for solution and injectionPfizer Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 27Document updated
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