nabumetone · Medicine question

How does nabumetone work to reduce pain and inflammation?

iatroX medicinesPublished 8 November 2026

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After absorption, nabumetone is rapidly converted in the liver to its principal active metabolite, 6-methoxy-2-naphthylacetic acid (6-MNA), which strongly inhibits prostaglandin synthesis.

Sources for this answer

Nabumetone 500 mg film-coated TabletsTillomed Laboratories Ltd · emc · SmPC §4.1 Therapeutic Indications · Version 2Document updated 20 July 2023

Sources checked 8 November 2026

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