Answer
Mitomycin is activated into an alkylating agent that predominantly alkylates DNA and inhibits DNA synthesis; it also releases free peroxide radicals, particularly at higher doses, causing DNA breaks.
Sources for this answer
- Mitomycin medac, 40 mg, Powder and solvent for intravesical solutionmedac Pharma LLP · emc · SmPC §5.1 Pharmacodynamic properties · Version 9Document updated
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