Answer
Once alpha-galactosidase A reaches lysosomes, migalastat (from migalastat hydrochloride) dissociates from the enzyme forms associated with amenable mutations, restoring enzyme activity and enabling catabolism of GL-3 and related substrates.
Sources for this answer
- Galafold 123 mg hard capsulesAmicus Therapeutics UK Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 12Document updated
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