Answer
Marstacimab neutralises tissue factor pathway inhibitor (TFPI), which may enhance the extrinsic coagulation pathway and bypass intrinsic pathway deficiencies by increasing available free factor Xa, thereby increasing thrombin generation and promoting haemostasis.
Sources for this answer
- Hympavzi 150 mg solution for injection in pre-filled penPfizer Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 4Document updated
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