Answer
Lenacapavir sodium selectively binds between HIV-1 capsid protein subunits, inhibiting replication by blocking capsid-mediated nuclear uptake of proviral DNA, interfering with Gag/Gag-Pol function to reduce capsid subunit production and disrupt virus assembly and release, and disrupting capsid subunit association to produce malformed capsids.
Sources for this answer
- Sunlenca 464 mg solution for injectionGilead Sciences Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 6Document updated
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