Answer
Ledipasvir/sofosbuvir increases plasma tenofovir concentrations when taken with tenofovir disoproxil succinate, especially with an HIV regimen also containing ritonavir or cobicistat as a pharmacokinetic enhancer.
Sources for this answer
- Tenofovir disoproxil Dr. Reddys 245 mg Film-Coated TabletsDr. Reddy's Laboratories (UK) Ltd · emc · SmPC §4.4 Special warnings and precautions for use · Version 12Document updated
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