Answer
Lamivudine + zidovudine are nucleoside analogues converted intracellularly to active 5′-triphosphates that act mainly as chain terminators of viral reverse transcription and selectively inhibit HIV-1 and HIV-2 replication in vitro.
Sources for this answer
- Combivir 150 mg/300 mg Film-coated TabletsViiV Healthcare UK Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 42Document updated
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