Answer
In an adult drug-interaction study, co-administration with ketoconazole, a potent P-gp inhibitor, increased nintedanib exposure 1.61-fold based on AUC and 1.83-fold based on Cmax.
Sources for this answer
- Vargatef 100 mg and 150 mg soft capsulesBoehringer Ingelheim Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 24Document updated
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