Answer
Itraconazole, a strong CYP3A inhibitor, increased imlunestrant AUC 2.11-fold and maximum concentration (Cmax) 1.87-fold; concomitant use should be avoided, or if unavoidable, the imlunestrant dose should be decreased by 200 mg once daily.
Sources for this answer
- Inluriyo 200 mg film-coated tabletsEli Lilly and Company Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 1Document updated
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