Answer
In healthy adults, itraconazole 200 mg once daily for 7 days given with a single 100 mg VITRAKVI (larotrectinib sulfate) dose increased larotrectinib peak plasma concentration (Cmax) 2.8-fold and overall exposure (AUC) 4.3-fold.
Sources for this answer
- Vitrakvi 25 mg hard capsulesBayer plc · emc · SmPC §4.5 Interaction with other medicinal products · Version 14Document updated
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