isotretinoin · Medicine question

How does isotretinoin affect sebaceous glands in severe acne?

iatroX medicinesPublished 8 November 2026

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Isotretinoin suppresses sebaceous gland activity and reduces gland size in severe acne, although its exact mechanism of action has not been fully elucidated.

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Isotretinoin 10 mg soft capsulesRanbaxy (UK) Limited a Sun Pharmaceutical Company · emc · SmPC §5.1 Pharmacodynamic properties · Version 12Document updated 26 June 2026

Sources checked 8 November 2026

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