Answer
Animal studies show that ioflupane binds with high affinity to presynaptic dopamine transporters, allowing radiolabelled ioflupane (123I) to serve as a surrogate marker for examining the integrity of dopaminergic nigrostriatal neurons.
Sources for this answer
- DaTSCAN 74 MBq/ml solution for injectionGE Healthcare Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 3Document updated
Sources checked