Answer
Inhaled mannitol in Osmohale increases airway osmolarity, triggering inflammatory cells in the airways to release bronchoconstriction mediators that act through specific receptors to contract bronchial smooth muscle and narrow the airways.
Sources for this answer
- Osmohale Inhalation Powder, Hard CapsulePharmaxis Europe Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 5Document updated
Sources checked