Answer
Icosapent ethyl lowers triglycerides by suppressing lipid-synthesising enzymes, increasing fatty acid oxidation and reducing microsomal triglyceride transfer protein to decrease hepatic triglyceride and VLDL synthesis and release, while increasing lipoprotein lipase expression to enhance triglyceride removal from circulating VLDL and chylomicrons.
Sources for this answer
- VazkepaRecordati Pharmaceuticals Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 4Document updated
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