hydroxyzine hydrochloride · Medicine question

How does hydroxyzine hydrochloride block the effects of histamine?

Name: How does hydroxyzine hydrochloride block the effects of histamine?
Published: 2026-11-08T01:51:12.100Z

iatroX medicinesPublished 8 November 2026

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Hydroxyzine hydrochloride competitively antagonises histamine at H1 receptors, inhibiting H1-mediated reactions such as vasodilation, flare, itching and sneezing.

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Hydroxyzine hydrochloride 10 mg film-coated tabletsMorningside Healthcare Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 1Document updated 12 June 2025

Sources checked 8 November 2026

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