Answer
Glecaprevir + pibrentasvir increases tacrolimus exposure, so the combination should be used cautiously with therapeutic drug monitoring and tacrolimus dose adjustment accordingly.
Sources for this answer
- Glecaprevir/Pibrentasvir 100 mg/40 mg film-coated tabletsAbbVie Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 25Document updated
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