Answer
In a clinical interaction study, Givlaari (givosiran sodium) increased caffeine Cmax 1.3-fold and AUC 3.1-fold, and dextromethorphan Cmax 2.0-fold and AUC 2.4-fold.
Sources for this answer
- GivlaariAlnylam UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 4Document updated
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