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Medicines GivinostatQuestion & answer

Givinostat · Medicine question

How does givinostat work in Duchenne muscular dystrophy?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Givinostat (Duvyzat) is a histone deacetylase inhibitor, but its precise mechanism of action in Duchenne muscular dystrophy is unknown.

Sources for this answer

Duvyzat 8.86 mg/mL oral suspensionITF Pharma Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 1Document updated 5 March 2025

Sources checked 8 November 2026

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More questions about Givinostat

What gastrointestinal adverse effects are common with Duvyzat (givinostat) in Duchenne muscular dystrophy?Can givinostat be used during pregnancy or breastfeeding?Has givinostat's effect on driving or using machines been tested?How much sodium benzoate does each mL of Duvyzat (givinostat) oral suspension contain?How should Duvyzat (givinostat) oral suspension be shaken before use?Should Duvyzat (givinostat) oral suspension be taken with food?

Givinostat

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