Answer
In healthy subjects, gemfibrozil increased roxadustat AUC 2.3-fold and Cmax 1.4-fold; haemoglobin should be monitored when gemfibrozil is started or stopped, with roxadustat dosing adjusted according to haemoglobin-based dose-adjustment rules.
Sources for this answer
- Evrenzo (roxadustat) 20, 50, 70, 100 and 150mg film-coated tabletsAstellas Pharma Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 6Document updated
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