Answer
Gefapixant citrate blocks ATP signalling through P2X3 receptors on airway sensory nerves, reducing excessive nerve activation and the excessive cough triggered by extracellular ATP.
Sources for this answer
- Lyfnua 45 mg film-coated tabletsMerck Sharp & Dohme (UK) Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 3Document updated
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