Answer
Ganciclovir, activated to ganciclovir triphosphate preferentially in virus-infected cells, competitively inhibits DNA polymerase-mediated incorporation of deoxyguanosine triphosphate into DNA and is incorporated into viral DNA, causing termination or very limited elongation.
Sources for this answer
- Cymevene_500mg_powder-for-concentrate-for-solution-for-infusionNeon Healthcare Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 7Document updated
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