Answer
Fosinopril sodium is converted to active fosinoprilat, which inhibits ACE, reducing angiotensin II formation and thereby reducing vasoconstriction and aldosterone secretion, potentially promoting sodium and fluid loss; ACE inhibition also prevents breakdown of bradykinin, contributing to blood-pressure reduction.
Sources for this answer
- Fosinopril sodium 10mg tabletsAurobindo Pharma - Milpharm Ltd. · emc · SmPC §5.1 Pharmacodynamic properties · Version 11Document updated
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