Answer
Foscarnet directly inhibits viral DNA polymerase and reverse transcriptase at concentrations that do not affect cellular DNA polymerases, without requiring activation by thymidine kinase or other kinases.
Sources for this answer
- Foscavir 24 mg/ml Solution for InfusionClinigen Healthcare Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 16Document updated
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