Answer
Fluvoxamine may decrease aminophylline hydrate clearance, increasing plasma theophylline concentrations and potential toxicity; concurrent use should usually be avoided, but if unavoidable, the theophylline dose should be halved and plasma levels monitored closely.
Sources for this answer
- Aminophylline hydrate 25mg/ml Solution for injectionADVANZ Pharma · emc · SmPC §4.5 Interaction with other medicinal products · Version 8Document updated
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