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Medicines fluconazoleQuestion & answer

fluconazole · Medicine question

How does fluconazole inhibit fungal ergosterol synthesis?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Fluconazole inhibits fungal cytochrome P-450-mediated 14-alpha-lanosterol demethylation, an essential step in fungal ergosterol biosynthesis.

Sources for this answer

Diflucan 150 CapsulesPfizer Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 26Document updated 6 May 2026

Sources checked 8 November 2026

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fluconazole

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