Answer
Etravirine, a non-nucleoside reverse transcriptase inhibitor, binds directly to HIV-1 reverse transcriptase and disrupts its catalytic site, blocking both RNA-dependent and DNA-dependent DNA polymerase activities.
Sources for this answer
- Intelence 100 mg tablets (Great Britain)Janssen-Cilag Ltd (a Johnson & Johnson Company) · emc · SmPC §5.1 Pharmacodynamic properties · Version 26Document updated
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