erenumab · Medicine question

How does erenumab act on the CGRP receptor?

iatroX medicinesPublished 8 November 2026

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Answer

Erenumab is a human monoclonal antibody that binds the CGRP receptor, potently and specifically competes with CGRP binding and inhibits its receptor function, with no significant activity against other calcitonin-family receptors.

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Aimovig solution for injection in pre filled penNovartis Pharmaceuticals UK Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 12Document updated 9 July 2026

Sources checked 8 November 2026

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Has an interaction between erenumab and sumatriptan been observed in healthy volunteers?Has erenumab been shown to interact with oral contraceptives containing ethinyl estradiol and norgestimate?How much polysorbate 80 does Aimovig (erenumab) solution for injection in a pre-filled pen contain per millilitre?Is erenumab known to pass into human breast milk?What does the product information recommend about using erenumab (Aimovig) during pregnancy?What serious allergic reactions have been reported with erenumab?

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