Answer
Emtricitabine/tenofovir alafenamide inhibits HIV replication after intracellular conversion to emtricitabine triphosphate and tenofovir diphosphate, respectively, which HIV reverse transcriptase incorporates into viral DNA, causing DNA chain termination.
Sources for this answer
- Emtricitabine/Tenofovir Alafenamide Gilead 200 mg/10 mg film coated tabletsGilead Sciences Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 25Document updated
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