Answer
Efavirenz lowers maraviroc exposure: efavirenz 600 mg once daily with maraviroc 100 mg twice daily reduced maraviroc AUC12 to 0.55 times and peak concentration (Cmax) to 0.49 times the levels without efavirenz.
Sources for this answer
- CELSENTRI 150 mg film-coated tabletsViiV Healthcare UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 35Document updated
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