dutasteride · Medicine question

How does dutasteride reduce dihydrotestosterone (DHT) levels?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Dutasteride reduces circulating dihydrotestosterone (DHT) by inhibiting both type 1 and type 2 5-alpha-reductase isoenzymes, which convert testosterone to DHT.

Sources for this answer

Avodart 0.5mg soft capsulesGlaxoSmithKline UK · emc · SmPC §5.1 Pharmacodynamic properties · Version 29Document updated 19 August 2026

Sources checked 8 November 2026

Explore this learning need in CPDTake this topic to CPD, then choose your learning context and available question library.

Can Avodart (dutasteride) capsules be taken with or without food?Do Avodart (dutasteride) soft capsules contain lecithin that may contain soya oil?Does dutasteride affect the pharmacokinetics of warfarin or digoxin?Has depression been reported as an adverse effect of dutasteride?How do verapamil and diltiazem affect dutasteride blood concentrations?Is dutasteride contraindicated in patients with severe hepatic impairment?

loading page…

Answer

Sources for this answer

More questions about dutasteride

Answer

Sources for this answer

More questions about dutasteride

dutasteride

More clinical questions?