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Medicines dronedarone hydrochlorideQuestion & answer

dronedarone hydrochloride · Medicine question

How does dronedarone affect digoxin exposure?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Dronedarone at 400 mg twice daily increases digoxin exposure by 2.5-fold by inhibiting the P-gp transporter.

Sources for this answer

Multaq 400mg tabletsSANOFI · emc · SmPC §4.5 Interaction with other medicinal products · Version 18Document updated 3 January 2025

Sources checked 8 November 2026

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dronedarone hydrochloride

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