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Medicines dornase alfaQuestion & answer

dornase alfa · Medicine question

How does dornase alfa thin mucus?

iatroX medicinesPublished 20 August 2026Reviewed 20 August 2026

The answer

Answer

It cuts extracellular DNA released by degenerating white blood cells, making cystic fibrosis sputum less sticky.

Sources for this answer

Pulmozyme 2500 U/ 2.5ml, nebuliser solutionemc · SmPC Current selected SmPC · Version 12

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dornase alfa

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More questions about dornase alfa

What is dornase alfa used for in cystic fibrosis?Does dornase alfa cure cystic fibrosis?How is dornase alfa inhaled?Can it be mixed with another nebuliser solution?Can it be continued during a chest infection?Why can mucus increase after starting treatment?

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