Answer
Donanemab is an IgG1 monoclonal antibody that binds N3pG Aβ, an insoluble, modified, N-terminal truncated form of amyloid beta found only in brain amyloid plaques, and aids plaque removal through microglial-mediated phagocytosis.
Sources for this answer
- Kisunla 350 mg concentrate for solution for infusionEli Lilly and Company Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 3Document updated
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