Answer
Diltiazem hydrochloride in Tildiem restricts calcium entry through slow channels and reduces calcium release from sarcoplasmic reticulum stores, lowering available intracellular calcium and myocardial oxygen consumption.
Sources for this answer
- Tildiem 60mg Modified-Release TabletsSANOFI · emc · SmPC §5.1 Pharmacodynamic properties · Version 26Document updated
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