Answer
In healthy subjects, diltiazem 240 mg once daily, a moderate CYP3A4 inhibitor, increased the AUC of co-administered daridorexant hydrochloride 25 mg by 2.4 times and its Cmax by 1.4 times.
Sources for this answer
- QUVIVIQ 50 mg film-coated tabletsIdorsia Pharmaceuticals UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 5Document updated
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